Contact us
|
Home
|
Login
| Users Online: 3642
Feedback
Subscribe
Advertise
Search
Advanced Search
Month wise articles
Figures next to the month indicate the number of articles in that month
2022
March
[
1
]
January
[
10
]
2021
December
[
7
]
November
[
9
]
September
[
8
]
August
[
2
]
July
[
1
]
June
[
4
]
May
[
3
]
April
[
4
]
March
[
7
]
February
[
3
]
January
[
6
]
2020
December
[
2
]
November
[
5
]
October
[
3
]
September
[
2
]
August
[
8
]
July
[
4
]
June
[
2
]
May
[
1
]
April
[
3
]
March
[
3
]
February
[
6
]
January
[
1
]
2019
December
[
6
]
November
[
4
]
September
[
4
]
August
[
3
]
July
[
6
]
June
[
1
]
May
[
2
]
April
[
6
]
March
[
3
]
February
[
4
]
January
[
2
]
2018
December
[
10
]
November
[
4
]
October
[
3
]
September
[
4
]
August
[
1
]
July
[
3
]
June
[
5
]
May
[
4
]
April
[
10
]
March
[
2
]
February
[
4
]
2017
December
[
5
]
November
[
4
]
October
[
3
]
September
[
9
]
July
[
5
]
June
[
2
]
May
[
4
]
April
[
6
]
March
[
6
]
February
[
7
]
2016
December
[
7
]
November
[
5
]
October
[
3
]
September
[
7
]
August
[
1
]
July
[
7
]
May
[
8
]
April
[
7
]
March
[
4
]
February
[
2
]
January
[
5
]
2015
November
[
4
]
October
[
5
]
September
[
5
]
August
[
4
]
July
[
3
]
June
[
19
]
May
[
5
]
April
[
1
]
March
[
5
]
February
[
9
]
January
[
3
]
2014
November
[
2
]
October
[
5
]
September
[
4
]
August
[
6
]
July
[
8
]
June
[
1
]
May
[
3
]
March
[
8
]
February
[
3
]
January
[
4
]
2013
December
[
5
]
November
[
2
]
October
[
4
]
September
[
4
]
August
[
3
]
July
[
3
]
June
[
5
]
May
[
7
]
March
[
18
]
February
[
1
]
January
[
1
]
2012
December
[
6
]
November
[
1
]
October
[
4
]
September
[
4
]
August
[
7
]
July
[
2
]
June
[
1
]
May
[
2
]
April
[
7
]
March
[
6
]
February
[
7
]
January
[
13
]
2011
December
[
3
]
November
[
1
]
October
[
7
]
August
[
9
]
July
[
3
]
June
[
7
]
May
[
3
]
March
[
6
]
February
[
8
]
January
[
6
]
2010
December
[
4
]
November
[
1
]
October
[
6
]
September
[
1
]
August
[
6
]
July
[
6
]
May
[
5
]
» Articles published in the past year
To view other articles click corresponding year from the navigation links on the left side.
All
|
Abstract
|
Book Review
|
Commentary
|
Editorial
|
Editorials
|
Letter
|
Original Articles
|
Research Article
|
Review Articles
|
Symposium - Original Research
|
Technical Note
Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
Show all abstracts
Show selected abstracts
Export selected to
Add to my list
Editorial:
A tribute to Jeffrey A. Kant, MD, PhD
Alexis B Carter, Rama R Gullapalli, Jill M Hagenkord, Hyunseok P Kang, Federico A Monzon, Thomas M Williams
J Pathol Inform
2012, 3:47 (31 December 2012)
DOI
:10.4103/2153-3539.105273
PMID
:23372988
[HTML Full text]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
[Sword Plugin for Repository]
Beta
Review Article:
Whole slide imaging for educational purposes
Liron Pantanowitz, Janusz Szymas, Yukako Yagi, David Wilbur
J Pathol Inform
2012, 3:46 (20 December 2012)
DOI
:10.4103/2153-3539.104908
PMID
:23372987
Digitized slides produced by whole slide image scanners can be easily shared over a network or by transferring image files to optical or other data storage devices. Navigation of digitized slides is interactive and intended to simulate viewing glass slides with a microscope (virtual microscopy). Image viewing software permits users to edit, annotate, analyze, and easily share whole slide images (WSI). As a result, WSI have begun to replace the traditional light microscope, offering a myriad of opportunities for education. This article focuses on current applications of WSI in education and proficiency testing. WSI has been successfully explored for graduate education (medical, dental, and veterinary schools), training of pathology residents, as an educational tool in allied pathology schools (e.g., cytotechnology), for virtual tracking and tutoring, tele-education (tele-conferencing), e-learning, virtual workshops, at tumor boards, with interactive publications, and on examinations. WSI supports flexible and cost-effective distant learning and augments problem-oriented teaching, competency evaluation, and proficiency testing. WSI viewed on touchscreen displays and with tablet technology are especially beneficial for education. Further investigation is necessary to develop superior WSI applications that better support education and to design viewing stations with ergonomic tools that improve the WSI-human interface and navigation of virtual slides. Studies to determine the impact of training pathologists without exposure to actual glass slides are also needed.
[ABSTRACT]
[HTML Full text]
[PDF]
[Mobile Full text]
[EPub]
[Citations (27) ]
[PubMed]
[Sword Plugin for Repository]
Beta
Review Article:
Experience with multimodality telepathology at the University of Pittsburgh Medical Center
Liron Pantanowitz, Clayton A Wiley, Anthony Demetris, Andrew Lesniak, Ishtiaque Ahmed, William Cable, Lydia Contis, Anil V Parwani
J Pathol Inform
2012, 3:45 (20 December 2012)
DOI
:10.4103/2153-3539.104907
PMID
:23372986
Several modes of telepathology exist including static (store-and-forward), dynamic (live video streaming or robotic microscopy), and hybrid technology involving whole slide imaging (WSI). Telepathology has been employed at the University of Pittsburgh Medical Center (UPMC) for over a decade at local, national, and international sites. All modes of telepathology have been successfully utilized to exploit our institutions subspecialty expertise and to compete for pathology services. This article discusses the experience garnered at UPMC with each of these teleconsultation methods. Static and WSI telepathology systems have been utilized for many years in transplant pathology using a private network and client-server architecture. Only minor clinically significant differences of opinion were documented. In hematopathology, the CellaVision
®
system is used to transmit, via email, static images of blood cells in peripheral blood smears for remote interpretation. While live video streaming has remained the mode of choice for providing immediate adequacy assessment of cytology specimens by telecytology, other methods such as robotic microscopy have been validated and shown to be effective. Robotic telepathology has been extensively used to remotely interpret intra-operative neuropathology consultations (frozen sections). Adoption of newer technology and increased pathologist experience has improved accuracy and deferral rates in teleneuropathology. A digital pathology consultation portal (https://pathconsult.upmc.com/) was recently created at our institution to facilitate digital pathology second opinion consults, especially for WSI. The success of this web-based tool is the ability to handle vendor agnostic, large image files of digitized slides, and ongoing user-friendly customization for clients and teleconsultants. It is evident that the practice of telepathology at our institution has evolved in concert with advances in technology and user experience. Early and continued adoption of telepathology has promoted additional digital pathology resources that are now being leveraged for other clinical, educational, and research purposes.
[ABSTRACT]
[HTML Full text]
[PDF]
[Mobile Full text]
[EPub]
[Citations (40) ]
[PubMed]
[Sword Plugin for Repository]
Beta
Review Article:
Custom software development for use in a clinical laboratory
John H Sinard, Peter Gershkovich
J Pathol Inform
2012, 3:44 (20 December 2012)
DOI
:10.4103/2153-3539.104906
PMID
:23372985
In-house software development for use in a clinical laboratory is a controversial issue. Many of the objections raised are based on outdated software development practices, an exaggeration of the risks involved, and an underestimation of the benefits that can be realized. Buy versus build analyses typically do not consider total costs of ownership, and unfortunately decisions are often made by people who are not directly affected by the workflow obstacles or benefits that result from those decisions. We have been developing custom software for clinical use for over a decade, and this article presents our perspective on this practice. A complete analysis of the decision to develop or purchase must ultimately examine how the end result will mesh with the departmental workflow, and custom-developed solutions typically can have the greater positive impact on efficiency and productivity, substantially altering the decision balance sheet. Involving the end-users in preparation of the functional specifications is crucial to the success of the process. A large development team is not needed, and even a single programmer can develop significant solutions. Many of the risks associated with custom development can be mitigated by a well-structured development process, use of open-source tools, and embracing an agile development philosophy. In-house solutions have the significant advantage of being adaptable to changing departmental needs, contributing to efficient and higher quality patient care.
[ABSTRACT]
[HTML Full text]
[PDF]
[Mobile Full text]
[EPub]
[Citations (12) ]
[PubMed]
[Sword Plugin for Repository]
Beta
Research Article:
Mouse cursor movement and eye tracking data as an indicator of pathologists' attention when viewing digital whole slide images
Vignesh Raghunath, Melissa O Braxton, Stephanie A Gagnon, Tad T Brunyé, Kimberly H Allison, Lisa M Reisch, Donald L Weaver, Joann G Elmore, Linda G Shapiro
J Pathol Inform
2012, 3:43 (20 December 2012)
DOI
:10.4103/2153-3539.104905
PMID
:23372984
Context:
Digital pathology has the potential to dramatically alter the way pathologists work, yet little is known about pathologists' viewing behavior while interpreting digital whole slide images. While tracking pathologist eye movements when viewing digital slides may be the most direct method of capturing pathologists' viewing strategies, this technique is cumbersome and technically challenging to use in remote settings. Tracking pathologist mouse cursor movements may serve as a practical method of studying digital slide interpretation, and mouse cursor data may illuminate pathologists' viewing strategies and time expenditures in their interpretive workflow.
Aims:
To evaluate the utility of mouse cursor movement data, in addition to eye-tracking data, in studying pathologists' attention and viewing behavior.
Settings and Design:
Pathologists (
N
= 7) viewed 10 digital whole slide images of breast tissue that were selected using a random stratified sampling technique to include a range of breast pathology diagnoses (benign/atypia, carcinoma
in situ
, and invasive breast cancer). A panel of three expert breast pathologists established a consensus diagnosis for each case using a modified Delphi approach.
Materials and Methods:
Participants' foveal vision was tracked using SensoMotoric Instruments RED 60 Hz eye-tracking system. Mouse cursor movement was tracked using a custom MATLAB script.
Statistical Analysis Used:
Data on eye-gaze and mouse cursor position were gathered at fixed intervals and analyzed using distance comparisons and regression analyses by slide diagnosis and pathologist expertise. Pathologists' accuracy (defined as percent agreement with the expert consensus diagnoses) and efficiency (accuracy and speed) were also analyzed.
Results:
Mean viewing time per slide was 75.2 seconds (SD = 38.42). Accuracy (percent agreement with expert consensus) by diagnosis type was: 83% (benign/atypia); 48% (carcinoma
in situ
); and 93% (invasive). Spatial coupling was close between eye-gaze and mouse cursor positions (highest frequency ∆x was 4.00px (SD = 16.10), and ∆y was 37.50px (SD = 28.08)). Mouse cursor position moderately predicted eye gaze patterns (
R
x = 0.33 and
R
y = 0.21).
Conclusions:
Data detailing mouse cursor movements may be a useful addition to future studies of pathologists' accuracy and efficiency when using digital pathology.
[ABSTRACT]
[HTML Full text]
[PDF]
[Mobile Full text]
[EPub]
[Citations (7) ]
[PubMed]
[Sword Plugin for Repository]
Beta
Original Article:
Tissue microarray design and construction for scientific, industrial and diagnostic use
Daniela Pilla, Francesca M Bosisio, Roberto Marotta, Stefano Faggi, Paolo Forlani, Maurizio Falavigna, Ida Biunno, Emanuele Martella, Pasquale De Blasio, Simone Borghesi, Giorgio Cattoretti
J Pathol Inform
2012, 3:42 (20 December 2012)
DOI
:10.4103/2153-3539.104904
PMID
:23372983
Context:
In 2013 the high throughput technology known as Tissue Micro Array (TMA) will be fifteen years old. Its elements (design, construction and analysis) are intuitive and the core histopathology technique is unsophisticated, which may be a reason why has eluded a rigorous scientific scrutiny. The source of errors, particularly in specimen identification and how to control for it is unreported. Formal validation of the accuracy of segmenting (also known as de-arraying) hundreds of samples, pairing with the sample data is lacking.
Aims:
We wanted to address these issues in order to bring the technique to recognized standards of quality in TMA use for research, diagnostics and industrial purposes.
Results:
We systematically addressed the sources of error and used barcode-driven data input throughout the whole process including matching the design with a TMA virtual image and segmenting that image back to individual cases, together with the associated data. In addition we demonstrate on mathematical grounds that a TMA design, when superimposed onto the corresponding whole slide image, validates on each and every sample the correspondence between the image and patient's data.
Conclusions:
High throughput use of the TMA technology is a safe and efficient method for research, diagnosis and industrial use if all sources of errors are identified and addressed.
[ABSTRACT]
[HTML Full text]
[PDF]
[Mobile Full text]
[EPub]
[Citations (9) ]
[PubMed]
[Sword Plugin for Repository]
Beta
Sitemap
|
What's New
Feedback
|
Copyright and Disclaimer
|
Privacy Notice
© Journal of Pathology Informatics | Published by Wolters Kluwer -
Medknow
Online since 10
th
March, 2010