Journal of Pathology Informatics Journal of Pathology Informatics
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Journal of Pathology Informatics

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Computer-assisted imaging algorithms facilitate histomorphometric quantification of kidney damage in rodent renal failure models
Marcin Klapczynski, Gerard D Gagne, Sherry J Morgan, Kelly J Larson, Bruce E LeRoy, Eric A Blomme, Bryan F Cox, Eugene W Shek
Introduction: Surgical 5/6 nephrectomy and adenine-induced kidney failure in rats are frequently used models of progressive renal failure. In both models, rats develop significant morphological...
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Estrogen receptor testing and 10-year mortality from breast cancer: A model for determining testing strategy
Christopher Naugler
Background: The use of adjuvant tamoxifen therapy in the treatment of estrogen receptor (ER) expressing breast carcinomas represents a major advance in personalized cancer treatment. Because th...
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Investigation into diagnostic agreement using automated computer-assisted histopathology pattern recognition image analysis
Joshua D Webster, Aleksandra M Michalowski, Jennifer E Dwyer, Kara N Corps, Bih-Rong Wei, Tarja Juopperi, Shelley B Hoover, R Mark Simpson
The extent to which histopathology pattern recognition image analysis (PRIA) agrees with microscopic assessment has not been established. Thus, a commercial PRIA platform was evaluated in two applicat...
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